Primate study adds to evidence of BPA harming human reproduction

ScienceDaily (Sep. 24, 2012) ? A Washington State University researcher has found new evidence that the plastic additive BPA can disrupt women's reproductive systems, causing chromosome damage, miscarriages and birth defects.

Writing in the journal Proceedings of the National Academy of Sciences, WSU geneticist Patricia Hunt and colleagues at WSU and the University of California, Davis, report seeing reproductive abnormalities in rhesus monkeys with BPA levels similar to those of humans. By using an animal with the most human-like reproductive system, the research bolsters earlier work by Hunt and others documenting widespread reproductive effects in rodents.

"The concern is exposure to this chemical that we're all exposed to could increase the risk of miscarriages and the risk of babies born with birth defects like Down Syndrome," says Hunt. "The really stunning thing about the effect is we're dosing grandma, it's crossing the placenta and hitting her developing fetus, and if that fetus is a female, it's changing the likelihood that that female is going to ovulate normal eggs. It's a three-for-one hit."

The research also adds to the number of organs affected by BPA, or bisphenol A, which is found in plastic bottles, the linings of aluminum cans and heat-activated cash register receipts. This May, Hunt was part of another paper in PNAS reporting that the additive altered mammary development in the primate, increasing the risk of cancer.

Hunt's colleagues at UC, Davis exposed different groups of gestating monkeys to single daily doses of BPA and low-level continuous doses and looked at how they affected the reproductive systems of female fetuses. She saw that in the earliest stage of the adult's egg development, the egg cell failed to divide properly. Earlier mouse studies showed similar disturbances translated into genetic defects in the mature egg.

A fertilized egg with the wrong number of chromosomes will almost always fail to come to term, leading to a spontaneous abortion or progeny with birth defects.

In monkeys exposed continuously, Hunt saw further complications in the third trimester as fetal eggs were not packaged appropriately in follicles, structures in which they develop. Eggs need to be packaged properly to grow, develop and mature.

"That's not good," says Hunt, "because it looks to us like you're just throwing away a huge number of the eggs that a female would have. It raises concerns about whether or not she's going to have a really short reproductive lifespan."

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The above story is reprinted from materials provided by Washington State University, via EurekAlert!, a service of AAAS.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.

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Journal Reference:

1. Patricia A. Hunt, Crystal Lawson, Mary Gieske, Brenda Murdoch, Helen Smith, Alyssa Marre, Terry Hassold, and Catherine A. VandeVoort. Bisphenol A alters early oogenesis and follicle formation in the fetal ovary of the rhesus monkey. PNAS, September 24, 2012 DOI: 10.1073/pnas.1207854109

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/living_well/~3/U3WeoVYQ_wc/120924152528.htm

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Three-year, 676-child clinical trial shows ... - Colorado Cancer Blogs

Clinical trial proves effectiveness of inexpensive mailed kits in boosting sun-protective behaviors. Image: Flickr/MonkeyMashButton

A blistering sunburn during childhood or adolescence more than doubles the adult risk of skin cancer. The accumulation of long-term sun exposure may be equally dangerous. A study from the Colorado School of Public Health and the University of Colorado Cancer Center recently published in the American Journal of Preventive Medicine shows one way to reduce this exposure: a double-blind randomized clinical trial of mailed sun protection packets led to higher frequency of sun protective behaviors including the use of long clothing, hats, shade, sunscreen, and midday sun avoidance.

?This is a low-cost, effective intervention that could be an important component in efforts to reduce sun exposure in children during the years that they acquire much of their risk for skin cancer,? says the paper?s first author, Lori Crane, PhD, MPH, CU Cancer Center investigator and chair of the Department of Community & Behavioral Health at the Colorado School of Public Health.

The study recruited 676 six-year-olds and their parents into the Colorado Kids Sun Care Program, half of whom completed phone interviews and other data collection, and half of whom also received intervention kits. Kits included newsletters and sun protection resources, such as swim shirts, hats, sunscreen and sun protection educational activities. They were mailed in April and May of the years 2005, 2006 and 2007, with the goal of guiding parents and children to ever-increasing stages of adopting sun-safe behaviors, from the early stage of ?unaware? to fully engaged and actively practicing. Phone interviews determined not only the level of sun-protective behaviors, but also parents? knowledge about melanoma, their evaluation of their child?s lifetime risk for the disease, and their opinion of skin cancer severity. Skin exams discovered children?s level of tanning and number of nevi ? the UV-influenced moles that can presage melanoma.

Across all measures of sun-protective behavior and awareness, the intervention group showed greater gains than the control group. Interestingly, the greatest increases were in the specific sun-protective behaviors emphasized in each yearly kit.

?After we emphasized long clothing in the spring of 2005, we saw a difference in clothing behavior in the summers of 2005 and 2006 not in 2007. Then after emphasizing hats in 2006, we saw a difference in hat use that year. And then after highlighting shade in 2007, we saw a corresponding increase in parents? awareness and use of shade as a sun-protective behavior,? Crane says.

In Crane?s opinion, this specific awareness and behavior change shows both the effectiveness of the intervention, but perhaps also the challenge of creating lasting behavior changes. Further study is needed to discover the durability of this intervention, and also how these increases in sun-protective behaviors influence skin cancer risk.

Crane and colleagues point out that although behavior changes in the trial were modest, the intervention was relatively inexpensive and, because it used postal mail, it could be readily delivered to a geographically broad population.

ClinicalTrials.gov identifier NCT01464957

This research was supported in part by National Cancer Institute grant R01-CA74592

Source: http://www.coloradocancerblogs.org/news/three-year-676-child-clinical-trial-shows-effectiveness-of-low-cost-intervention-to-improve-sun-protection

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Web Design in SW1 (Westminster, Belgravia & Pimlico) | Web ...

L. E. e-Consulting is a web design company operating in SW1 (Westminster, Belgravia & Pimlico) which is specialized in the development of professional-looking?websites and the ranking of websites on search engines.

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Source: http://www.webservicesconsultancy.com/blog/web-design-sw1-westminster-belgravia-pimlico/

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Makkah seeks to build renewable energy plant

Riyadh: Makkah is working toward becoming the first city in Saudi Arabia to operate a utility-scale plant generating electricity from renewables.

The city on January 5 plans to select from a group of at least 20 bidders competing to build and operate facilities producing 385 gigawatt-hours per year of power, including 100 megawatts of solar capacity, Mayor Osama Al Bar said.

?No city in Saudi Arabia owns power-generation assets, and we want to be the first city that owns power plants and hopefully the first in the Muslim world,? Al Bar said in an interview on September 16 in Riyadh.

The plans are the latest indication that the kingdom is stepping up efforts to diversify its sources of energy as economic and population growth threaten to erode Saudi Arabia?s status as the world?s biggest oil exporter.

Article continues below

The central government is seeking $109 billion (Dh400.3 billion) of investment for building a solar industry, aiming to get a third of Saudi Arabia?s power from the sun by 2032 compared with almost none now. The target is almost as much as the $136 billion invested worldwide in solar energy last year, according to Bloomberg New Energy Finance.

Makkah?s programme complements that work and may provide a guide for other Middle Eastern cities on how to adopt the technology, Adnan Amin, director general of the International Renewable Energy Agency, said.

?The project is very visionary as Makkah has special significance around the world,? Amin, from the Abu Dhabi-based industry organisation, said in London on September 18. ?The case is very simple. In 25 years, they [Saudi Arabia] could become net importers of energy. That makes renewables comparatively cheaper.?

Makkah is located 70 kilometres inland south of the Red-Sea port of Jeddah. The city has around 2 million residents and it hosts more than triple that number every year.

Saudi Arabia depends on oil for 86 per cent of its annual revenue and is accelerating exploration for natural gas and planning to develop solar and nuclear power to preserve more of its valuable crude for export. Less than 1 per cent of its energy came from renewables last year, according to data from BP Plc.

The nation gets more than twice the sunshine of anywhere in Europe and about as much as the brightest parts of the south-western US Research at the King Fahd University of Petroleum & Minerals in Dhahran estimated Saudi solar radiation between 4.5 to 7 kilowatts per square metre a day in the Kingdom. Greece by comparison measured 1.7 kilowatts, according to the European Photovoltaic Industry Association.

The Saudi programme is being managed by the King Abdullah City for Atomic and Renewable Energy, a government-backed institution independent of the energy ministry and Saudi Arabian Oil Co., the state oil company known as Aramco.

In Makkah, groups competing for the work include Saudi Binladin Group and ACWA Power International, the mayor said. Work on the project should start in June next year with completion within five years.

Some of the facilities will be fuelled by a mix of fossil fuel, wind, or biomass, Al Bar said. The electricity from the project will be used for lighting and in 35 tunnels, helping defray some of the 100 million riyals (Dh97.69 million) a year Makkah spends on electricity. The province is the biggest power consumer among Saudi Arabia?s 13 regions.

?We are open to all options, but solar must be there and then other renewable sources can go into the mix,? he said. Makkah produces 4,000 metric tonnes a day of garbage that also can be fed into power plants, Al Bar said.

Growing electricity demand

Saudi Arabia?s electricity demand is growing 8 per cent a year to keep up with a 3.2 per cent annual increase in the population, which numbered more than 25 million in 2011, according to government figures. Makkah hosted 5.8 million pilgrims in the first nine months of this year and expects another 1.8 million visitors by the end of 2012.

The Kingdom aims to generate as much energy from solar cells as it pumps out of the ground to export in the form of crude, Oil Minister Ali Al Naimi said in a speech in Poland in June 2011. He said the nation has the potential to produce enough solar power to meet four times current world electricity demand.

The developer on the Makkah solar contracts will be able to operate the plants until it can recoup its investment, the mayor said. The bidder offering the shortest contractual period will win the business, according to Makkah?s municipal authorities.

?During the build-own-transfer contract duration, generators will be selling electricity to Saudi Electricity Co., and after the contract ends, the city will own the power plants and it will sell electricity just like any other independent producer in the country,? he said.

The Kingdom currently has about 3 megawatts of solar installations, trailing Egypt, Morocco, Tunisia, Algeria and the UAE, according to Bloomberg New Energy Finance.

The Saudi government targets 41,000 megawatts of solar capacity within two decades. That would save as much as 523,000 barrels a day of oil equivalent, according to Ka-Care.

That target is ?not just a short-term measure to meet energy demand,? Amin of the Irena industry group said.

?It?s a strategic approach through which Saudis are slowly beginning to compensate for internal consumption and to develop the possibility that they can become exporters of renewable energy, particularly solar,? he said. ?It?s at the beginning point, but it?s happening.?

Source: http://gulfnews.com/makkah-seeks-to-build-renewable-energy-plant-1.1080233?localLinksEnabled=false&utm_source=Feeds&utm_medium=RSS&utm_term=%3C!%5BCDATA%5BBusiness_RSS_feed%5D%5D%3E&utm_content=1.1080233&utm_campaign=%3C!%5BCDATA%5BMakkah_seeks_t

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Statement from White House Drug Policy Director Kerlikowske on ...

Washington, D.C.--(ENEWSPF)--September 24, 2012. ?Today, Gil Kerlikowske, Director of National Drug Control Policy (ONDCP) released the following statement in response to survey data from the Department of Health and Human Services? (HHS) Substance Abuse and Mental Health Services Administration (SAMHSA) showing significant declines in the non-medical use of prescription drugs:

?These results are encouraging, but we cannot afford to take our eyes off the ball.? The abuse of painkillers in America continues to take too many lives, tear apart too many families, and place too many burdens on communities across the nation.?? According to the Centers for Disease Control and Prevention, prescription drug abuse remains an epidemic.?

The good news is that today?s findings prove yet again that we are not powerless against the problem of substance abuse in America.?Since day one, the Obama Administration has pursued a bipartisan and holistic approach to this challenge.?I am heartened by this progress because it shows that our prescription drug abuse action plan is working to make America healthier and safer. We still have more work to do, but we remain steadfast in our commitment to reversing this epidemic through a balanced approach.?

According to new data from the National Survey on Drug Use and Health (NSDUH), the number of young adults (people aged 18 to 25) who used prescription drugs for non-medical purposes in the past month declined 14 percent -- from 2 million in 2010 to 1.7 million in 2011. This decline has driven an overall 12 percent decline in the number of Americans abusing prescription drugs.??

To address the problem of prescription drug abuse, the Administration has released Epidemic: Responding to America's Prescription Drug Abuse Crisis. A national framework for reducing prescription drug diversion and abuse, the plan supports the expansion of state-based prescription drug monitoring programs, more convenient and environmentally responsible disposal methods to remove unused medications from the home, education for patients and healthcare providers, and reducing the prevalence of pill mills and doctor shopping through enforcement efforts.

The number of The National Survey on Drug Use and Health is a scientifically conducted annual survey of approximately 70,000 people throughout the country, aged 12 and older.? Because of its statistical power, it is the nation?s premier source of statistical information on the scope and nature of many substance abuse and mental health issues affecting the nation. The complete survey findings are available on the SAMHSA web site at: for more information about SAMHSA visit: http://www.samhsa.gov/

For more information on Administration drug policy and efforts to reduce drug use and its consequences visit www.WhiteHouse.gov/ONDCP

Source: whitehouse.gov/ondcp

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Drug Czar Ignores Failure Of Marijuana Prohibition To Curb Use

Source: http://www.enewspf.com/latest-news/health-and-fitness/36797-statement-from-white-house-drug-policy-director-kerlikowske-on-hhs-report-showing-declines-in-prescription-drug-abuse.html

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Very confused and broken down.. - Talk About Marriage

Anxiety, Depression and Relationships Marriage and relationships are difficult by themselves, but coping with anxiety and depression can make them even more challenging.

Today, 04:08 PM	? #2 (permalink)
Member ? Join Date: Dec 2011 Location: Canada Posts: 1,586	Sorry for where you are,but if what you're doing goes against your core values then you will have many regrets.You're in an EA with another man and it feels so good and right,probably the same way you once felt with your H when your relationship first started.That's the brain chemistry going haywire from the newness of it all. All you share with OM is happy times far removed from the perceived drudgery of your marriage.The more you get involved.the easier it becomes to find faults in your marriage even to the point of rewriting some of the marital history.Your H can't compete or work towards a solution because he doesn't even know he's competing.You think you know this OM,but do you really? This is a man who intends to take another man's wife like a thief in the night and all it really takes is a little attention and a few sweet words.The sad thing is you seem willing to abet him in it by destroying and betraying a man who up until the past couple of years was there for not only the highs in your marriage but faced life's everyday hurdles with you. I don't know what you will do but you might be better served investing the energy you give the OM on finding real solutions to your problems that are far more respectful than what you're doing now.Marriage responsibility is something that's shared,but cheating,well that's !00% on the cheater and there is no excuse for it....there are other options if you're not happy. Hope you come clean and try to work it out with your H because if you don't you may,as others have before you,realize too late that the grass isn't always greener.Take care. __________________ "Truth is like the sun,you can shut it out for a time,but it ain't going away"-Elvis
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Today, 05:28 PM	? #4 (permalink)
Member ? Join Date: May 2012 Location: Michigan Posts: 2,482	Wantmyselfback, I have been there. Believe me when I say that an emotional affair is NOT the answer. My husband treated me like I was a kid, often. He was always angry, always yelling... then he finally got the right diagnoses and is on his way to getting his medications adjusted properly. It's like he is a totally different man than the one he was when I was in my EAs. He isn't the same man he was 13 years ago, but he is SO far from the man he was last year at this time...even two years ago! WMB, I know this OM is saying he loves you and wants to be with you, etc. Again, I've been there. I heard the words, I got the butterflies, I had those feelings. But the thing is, your OM isn't there day to day. He is showing you his best side, ostensibly to help you through this difficult time in your life. Unfortunately, in acting the way he is, he is encouraging you to cheat on your husband, which you are doing now. Regarding your husband, what is going on with him? Has he been diagnosed with a mental/psychological illness? Is he receiving care from a psychiatrist or psychologist? If he has psych diagnoses, but is not being medicated properly, you will have this mean man to contend with, as I did. Please, for you sanity, don't continue in this affair. It isn't worth it to be labeled a cheater.
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Today, 07:45 PM	? #6 (permalink)
Member ? Join Date: May 2012 Location: Michigan Posts: 2,482	Yes, I know where you are coming from. My OM had things he could have told my husband, etc. But, I told my husband anyway. In the end, I felt it was better to come clean, deal with the consequences, and hope for the best with my husband. It could have gone the other way, but it didn't. Telling him DID scare the hell out of me, for sure! But it was the right decision. I'm guessing the pics were either naked, or barely clothed, or both? Well, if you decide that you want to give your marriage a go, and I mean REALLY work on it, you need to tell him everything. But that's the big thing... you are in the fog of the affair, and the only way you can even try to work on the marriage is if the OM is out of the picture. Your last sentence tells me that there may still be hope for your marriage: "I can't help but think my world would end if he left."... I know how that feels. But, in order to continue with him, you need to be honest with him... no matter how hard it is.
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Find a Therapist:

Source: http://talkaboutmarriage.com/anxiety-depression-relationships/56607-very-confused-broken-down.html

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? Avon Walk for Breast Cancer: GOOD MORNING SANTA BARBARA WALKERS & CREW!! Thank you for being here and for you...

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Source: http://www.facebook.com/avonwalks/posts/471919049507844

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